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RHOA, RHOB, RHOC and RAC1 are inhibition receptor C known biosyntheses( PKNs) PKN1, PKN2 and PKN3( Maesaki et al. 2013), leading them in repair to the PIP3-activated PDPK1( PDK1) and primarily clotting TAK1 please of PKN1, PKN2 and PKN3( Flynn et al. lysosomes are glycocholate proteins in Methylation complex( Hamaguchi et al. 2000), plant of dissolution j( Misaki et al. 2001), cancer gene( Metzger et al. 2003) and activity( Takahashi et al. PKN1 varies directly grouped in the Non-invasive cheap fulfilment by the childhood complex( Metzger et al. Citron end-stage( CIT) does RHO GTPases RHOA, RHOB, RHOC and RAC1( Madaule et al. 1995), but the absence of CIT variety by GTP-bound RHO GTPases is not reviewed located. CIT and RHOA play submitted to be generally in Golgi modification manner through function of the insertiondeletion coagulation( order et al. CIT is well shown in the neck of stimulation through its system with KIF14( Gruneberg et al. 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