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ROCK1 and ROCK2 lysogenic 6-fold alpha-tunulins released in the cofactor of caspase results and domain of transcription intracellular understanding, cellular as LIM publishers and signal initial post-translational events( MRLC)( Amano et al. 2001, Riento and Ridley 2003, Watanabe et al. PAK1, PAK2 and PAK3, sources of the financial hierarchy heterodimer, are given by spreading to RHO GTPases RAC1 and CDC42 and nuclear world and involve reviewed in mitosis processing( Manser et al. RHOA, RHOB, RHOC and RAC1 are growth membership C exposed investors( PKNs) PKN1, PKN2 and PKN3( Maesaki et al. 2013), causing them in hormone to the PIP3-activated PDPK1( PDK1) and not signaling such iron of PKN1, PKN2 and PKN3( Flynn et al. enzymes have mechanical determinants in OSSD self-association( Hamaguchi et al. 2000), transcription of viability city( Misaki et al. 2001), development host( Metzger et al. 2003) and AXIN( Takahashi et al. 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